stimulant
Amphetamine dosage 2026: safe ranges by route and weight.
Amphetamine has 2 documented routes of administration. The most common is oral. Always start at the lowest dose range and wait the full onset window before redosing.
Dose ranges by route.
Oral
- Threshold
- 5 mg
- Light
- 10–20 mg
- Common
- 20–40 mg
- Strong
- 40–80 mg
- Heavy
- 80 mg
Insufflated
- Threshold
- 5 mg
- Light
- 10–20 mg
- Common
- 20–40 mg
- Strong
- 40–70 mg
- Heavy
- 70 mg
| Route | Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|---|
| Oral | 5 mg | 10–20 mg | 20–40 mg | 40–80 mg | 80 mg |
| Insufflated | 5 mg | 10–20 mg | 20–40 mg | 40–70 mg | 70 mg |
Start at the bottom. Body chemistry, tolerance, and combinations all matter.
Duration timeline.
Oral
total ~ 1290 min- Onset
- 30–90 min
- Peak
- 2–4h
- Offset
- 2–4h
- After
- 3–12h
Insufflated
total ~ 855 min- Onset
- 5–15 min
- Peak
- 60–180 min
- Offset
- 2–3h
- After
- 2–8h
Bodyweight quick formula
For a 70 kg adult, divide the total mg dose by 70 to get your mg/kg ratio. Most published ranges assume this reference weight. If you weigh significantly less, reduce proportionally; significantly more does not always mean linearly higher doses.
Related pages
FAQ.
- What is a safe Amphetamine dose?
- A "safe" dose depends on body weight, tolerance, set and setting. Start at the threshold or light range for your chosen route and do not redose until onset is complete.
- How do I calculate Amphetamine dose by weight?
- For substances where bodyweight matters: divide the mg amount by your weight in kg to get the mg/kg ratio. Most common dose data assumes a 70–80 kg adult.
- What happens if I take too much Amphetamine?
- Exceeding the "heavy" range significantly increases risk of adverse effects, medical emergency, or overdose. Harm reduction starts with knowing the ranges.
- How long does Amphetamine last?
- Duration varies by route. The timeline section below shows onset, peak, offset and after-effects for each route.
- Can I mix Amphetamine with other substances?
- Many combinations are dangerous. Check the interaction checker tool before combining anything. Never combine on a first experience.
- Is Amphetamine dosage the same for all routes?
- No. Bioavailability differs significantly by route — intranasal and IV routes typically require lower doses than oral for equivalent effect.
- Should I weigh my Amphetamine dose?
- Always. A milligram scale (0.001g precision) is essential for most substances. Volumetric dosing with a solvent is the gold standard for sub-10mg doses.