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psychedelic

DMT dosage 2026: safe ranges by route and weight.

DMT has 3 documented routes of administration. The most common is smoked. Always start at the lowest dose range and wait the full onset window before redosing.

Dose ranges by route.

Smoked
Threshold
5 mg
Light
10–20 mg
Common
20–40 mg
Strong
40–60 mg
Heavy
60 mg
Vaporized
Threshold
5 mg
Light
10–20 mg
Common
20–40 mg
Strong
40–60 mg
Heavy
60 mg
Oral
Threshold
50 mg
Light
75–150 mg
Common
150–300 mg
Strong
300–500 mg
Heavy
500 mg

Start at the bottom. Body chemistry, tolerance, and combinations all matter.

Duration timeline.

Smoked

total ~ 76 min
Onset: 0–1 minPeak: 2–5 minOffset: 5–10 minAfter: 15–60 min
Onset
0–1 min
Peak
2–5 min
Offset
5–10 min
After
15–60 min

Vaporized

total ~ 76 min
Onset: 0–1 minPeak: 2–5 minOffset: 5–10 minAfter: 15–60 min
Onset
0–1 min
Peak
2–5 min
Offset
5–10 min
After
15–60 min

Oral

total ~ 720 min
Onset: 20–60 minPeak: 60–120 minOffset: 1.5–3hAfter: 3–6h
Onset
20–60 min
Peak
60–120 min
Offset
1.5–3h
After
3–6h

Bodyweight quick formula

For a 70 kg adult, divide the total mg dose by 70 to get your mg/kg ratio. Most published ranges assume this reference weight. If you weigh significantly less, reduce proportionally; significantly more does not always mean linearly higher doses.

Related pages


FAQ.

What is a safe DMT dose?
A "safe" dose depends on body weight, tolerance, set and setting. Start at the threshold or light range for your chosen route and do not redose until onset is complete.
How do I calculate DMT dose by weight?
For substances where bodyweight matters: divide the mg amount by your weight in kg to get the mg/kg ratio. Most common dose data assumes a 70–80 kg adult.
What happens if I take too much DMT?
Exceeding the "heavy" range significantly increases risk of adverse effects, medical emergency, or overdose. Harm reduction starts with knowing the ranges.
How long does DMT last?
Duration varies by route. The timeline section below shows onset, peak, offset and after-effects for each route.
Can I mix DMT with other substances?
Many combinations are dangerous. Check the interaction checker tool before combining anything. Never combine on a first experience.
Is DMT dosage the same for all routes?
No. Bioavailability differs significantly by route — intranasal and IV routes typically require lower doses than oral for equivalent effect.
Should I weigh my DMT dose?
Always. A milligram scale (0.001g precision) is essential for most substances. Volumetric dosing with a solvent is the gold standard for sub-10mg doses.