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Psilocybin mushrooms dosage 2026: safe ranges by route and weight.

Psilocybin mushrooms has 1 documented route of administration. The most common is oral. Always start at the lowest dose range and wait the full onset window before redosing.

Dose ranges by route.

Oral
Threshold
0.25 g
Light
0.5–1 g
Common
1–2.5 g
Strong
2.5–5 g
Heavy
5 g

Start at the bottom. Body chemistry, tolerance, and combinations all matter.

Duration timeline.

Oral

total ~ 730 min
Onset: 10–40 minPeak: 60–150 minOffset: 60–180 minAfter: 2–6h
Onset
10–40 min
Peak
60–150 min
Offset
60–180 min
After
2–6h

Related pages

Full Psilocybin mushrooms profileEffects, interactions, testing, legal statusDosage calculatorInteractive tool with colour-coded zonesInteraction checkerCheck pairwise safety before combiningRelated: lsdCompare dosage profiles

FAQ.

What is a safe Psilocybin mushrooms dose?
A "safe" dose depends on body weight, tolerance, set and setting. Start at the threshold or light range for your chosen route and do not redose until onset is complete.
How do I calculate Psilocybin mushrooms dose by weight?
For substances where bodyweight matters: divide the mg amount by your weight in kg to get the mg/kg ratio. Most common dose data assumes a 70–80 kg adult.
What happens if I take too much Psilocybin mushrooms?
Exceeding the "heavy" range significantly increases risk of adverse effects, medical emergency, or overdose. Harm reduction starts with knowing the ranges.
How long does Psilocybin mushrooms last?
Duration varies by route. The timeline section below shows onset, peak, offset and after-effects for each route.
Can I mix Psilocybin mushrooms with other substances?
Many combinations are dangerous. Check the interaction checker tool before combining anything. Never combine on a first experience.
Is Psilocybin mushrooms dosage the same for all routes?
No. Bioavailability differs significantly by route — intranasal and IV routes typically require lower doses than oral for equivalent effect.
Should I weigh my Psilocybin mushrooms dose?
Always. A milligram scale (0.001g precision) is essential for most substances. Volumetric dosing with a solvent is the gold standard for sub-10mg doses.