Comparison
2C-B vs MDMA.
Side-by-side comparison of 2C-B and MDMA — dosage, effects, duration, legal status, and key harm reduction considerations.
- Category2C-BpsychedelicMDMAempathogen
- Chemical class2C-BphenethylamineMDMAsubstituted-amphetamine
- Common dose2C-B15–25 mgMDMA75–125 mg
- Peak duration2C-B120–240 minMDMA90–150 min
- Primary positives2C-BVisuales abiertos y cerrados muy nítidos, Euforia y risa en dosis media, Calidez tipo MDMA en el extremo bajo, psicodélico en el altoMDMAEuforia, Calidez emocional y apertura, Empatía aumentada
- Primary negatives2C-BNáuseas y molestias estomacales 30–60 min después (oral), Quemazón fuerte al esnifar, Ansiedad en dosis altas, sobre todo con estimulantesMDMABruxismo (apretar la mandíbula), Deshidratación o hiponatremia por exceso de agua, Hipertermia en ambientes calurosos
- Legal (DE)2C-BprohibitedMDMAillegal
- Legal (NL)2C-Bschedule-1MDMAillegal-tolerated
- Legal (US)2C-Bschedule-1MDMAschedule-1
- Legal (UK)2C-Bclass-aMDMAclass-a
| 2C-B | MDMA | |
|---|---|---|
| Category | psychedelic | empathogen |
| Chemical class | phenethylamine | substituted-amphetamine |
| Common dose | 15–25 mg | 75–125 mg |
| Peak duration | 120–240 min | 90–150 min |
| Primary positives | Visuales abiertos y cerrados muy nítidos, Euforia y risa en dosis media, Calidez tipo MDMA en el extremo bajo, psicodélico en el alto | Euforia, Calidez emocional y apertura, Empatía aumentada |
| Primary negatives | Náuseas y molestias estomacales 30–60 min después (oral), Quemazón fuerte al esnifar, Ansiedad en dosis altas, sobre todo con estimulantes | Bruxismo (apretar la mandíbula), Deshidratación o hiponatremia por exceso de agua, Hipertermia en ambientes calurosos |
| Legal (DE) | prohibited | illegal |
| Legal (NL) | schedule-1 | illegal-tolerated |
| Legal (US) | schedule-1 | schedule-1 |
| Legal (UK) | class-a | class-a |
Key harm-reduction difference
2C-B and MDMA differ most in their risk profiles and durations. Always research each independently before any session. If you are choosing between them based on safety alone, consult the full profiles and the interaction checker for any combinations you may be planning.
Related pages
FAQ.
- Is 2C-B stronger than MDMA?
- "Stronger" depends on the metric. Compare dose ranges, subjective intensity, and duration side by side above. Always factor in individual tolerance.
- Can I combine 2C-B and MDMA?
- Check the interaction checker for this specific pair. Many combinations carry serious risk even at low doses.
- Which lasts longer, 2C-B or MDMA?
- Duration varies by route. See the comparison table above for peak and total duration by the most common route.
- 2C-B vs MDMA: which is safer?
- Neither substance is "safe" in absolute terms. Harm is a function of dose, setting, purity, and individual factors. The comparison above covers the key risk differences.
- Are 2C-B and MDMA in the same drug class?
- See the category and chemical class rows above. Substances in different classes often have very different risk profiles even if subjective effects overlap.
- Is 2C-B legal where MDMA is?
- Legal status is substance- and jurisdiction-specific. See the legal status section for key countries.
- Where can I get harm reduction info for 2C-B and MDMA?
- Each substance has a full profile on this site with dosage, interactions, testing, and legal information. Follow the links at the bottom of this page.
- How do I test whether my substance is 2C-B or MDMA?
- Reagent testing can distinguish most substances. Check the reagent guide tool for expected color reactions for both.