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Comparison

Kétamine vs MDMA.

Side-by-side comparison of Kétamine and MDMA — dosage, effects, duration, legal status, and key harm reduction considerations.

  • Category
    Kétamine
    dissociative
    MDMA
    empathogen
  • Chemical class
    Kétamine
    arylcyclohexylamine
    MDMA
    substituted-amphetamine
  • Common dose
    Kétamine
    50–100 mg
    MDMA
    75–125 mg
  • Peak duration
    Kétamine
    30–45 min
    MDMA
    90–150 min
  • Primary positives
    Kétamine
    Euphorie, Dissociation corporelle, Amplification de la musique et des sons
    MDMA
    Euphorie, Chaleur émotionnelle et ouverture, Empathie accrue
  • Primary negatives
    Kétamine
    Ataxie sévère (perte de coordination motrice) à fortes doses, Nausées, surtout combinée à la nourriture ou à l'alcool, K-hole (dissolution intense de l'ego / expérience hors du corps)
    MDMA
    Bruxisme (crispation des mâchoires), Déshydratation ou hyponatrémie par surhydratation, Hyperthermie en environnement chaud
  • Legal (DE)
    Kétamine
    prescription-only
    MDMA
    illegal
  • Legal (NL)
    Kétamine
    schedule-1
    MDMA
    illegal-tolerated
  • Legal (US)
    Kétamine
    schedule-3
    MDMA
    schedule-1
  • Legal (UK)
    Kétamine
    class-b
    MDMA
    class-a

Key harm-reduction difference

Kétamine and MDMA differ most in their risk profiles and durations. Always research each independently before any session. If you are choosing between them based on safety alone, consult the full profiles and the interaction checker for any combinations you may be planning.

Related pages


FAQ.

Is Kétamine stronger than MDMA?
"Stronger" depends on the metric. Compare dose ranges, subjective intensity, and duration side by side above. Always factor in individual tolerance.
Can I combine Kétamine and MDMA?
Check the interaction checker for this specific pair. Many combinations carry serious risk even at low doses.
Which lasts longer, Kétamine or MDMA?
Duration varies by route. See the comparison table above for peak and total duration by the most common route.
Kétamine vs MDMA: which is safer?
Neither substance is "safe" in absolute terms. Harm is a function of dose, setting, purity, and individual factors. The comparison above covers the key risk differences.
Are Kétamine and MDMA in the same drug class?
See the category and chemical class rows above. Substances in different classes often have very different risk profiles even if subjective effects overlap.
Is Kétamine legal where MDMA is?
Legal status is substance- and jurisdiction-specific. See the legal status section for key countries.
Where can I get harm reduction info for Kétamine and MDMA?
Each substance has a full profile on this site with dosage, interactions, testing, and legal information. Follow the links at the bottom of this page.
How do I test whether my substance is Kétamine or MDMA?
Reagent testing can distinguish most substances. Check the reagent guide tool for expected color reactions for both.