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Ketamine dosage 2026: safe ranges by route and weight.

Ketamine has 3 documented routes of administration. The most common is insufflated. Always start at the lowest dose range and wait the full onset window before redosing.

Dose ranges by route.

Burundan çekilen
Eşik
10 mg
Hafif
20–50 mg
Olağan
50–100 mg
Güçlü
100–150 mg
Ağır
150 mg
Ağızdan
Eşik
40 mg
Hafif
75–150 mg
Olağan
150–300 mg
Güçlü
300–450 mg
Ağır
450 mg
Intramuscular
Eşik
10 mg
Hafif
15–40 mg
Olağan
40–75 mg
Güçlü
75–125 mg
Ağır
125 mg

Alttan başla. Vücut, tolerans ve karışımlar her şeyi değiştirir.

Duration timeline.

Burundan çekilen

toplam ~ 340 min
Başlangıç: 5–10 minZirve: 30–45 minİniş: 30–45 minSonrası: 60–240 min
Başlangıç
5–10 min
Zirve
30–45 min
İniş
30–45 min
Sonrası
60–240 min

Ağızdan

toplam ~ 600 min
Başlangıç: 10–30 minZirve: 45–90 minİniş: 60–120 minSonrası: 2–6h
Başlangıç
10–30 min
Zirve
45–90 min
İniş
60–120 min
Sonrası
2–6h

Intramuscular

toplam ~ 245 min
Başlangıç: 1–5 minZirve: 20–30 minİniş: 20–30 minSonrası: 60–180 min
Başlangıç
1–5 min
Zirve
20–30 min
İniş
20–30 min
Sonrası
60–180 min

Bodyweight quick formula

For a 70 kg adult, divide the total mg dose by 70 to get your mg/kg ratio. Most published ranges assume this reference weight. If you weigh significantly less, reduce proportionally; significantly more does not always mean linearly higher doses.

Related pages


FAQ.

What is a safe Ketamine dose?
A "safe" dose depends on body weight, tolerance, set and setting. Start at the threshold or light range for your chosen route and do not redose until onset is complete.
How do I calculate Ketamine dose by weight?
For substances where bodyweight matters: divide the mg amount by your weight in kg to get the mg/kg ratio. Most common dose data assumes a 70–80 kg adult.
What happens if I take too much Ketamine?
Exceeding the "heavy" range significantly increases risk of adverse effects, medical emergency, or overdose. Harm reduction starts with knowing the ranges.
How long does Ketamine last?
Duration varies by route. The timeline section below shows onset, peak, offset and after-effects for each route.
Can I mix Ketamine with other substances?
Many combinations are dangerous. Check the interaction checker tool before combining anything. Never combine on a first experience.
Is Ketamine dosage the same for all routes?
No. Bioavailability differs significantly by route — intranasal and IV routes typically require lower doses than oral for equivalent effect.
Should I weigh my Ketamine dose?
Always. A milligram scale (0.001g precision) is essential for most substances. Volumetric dosing with a solvent is the gold standard for sub-10mg doses.