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Comparison

LSD vs Psilocybin mushrooms.

Side-by-side comparison of LSD and Psilocybin mushrooms — dosage, effects, duration, legal status, and key harm reduction considerations.

  • Category
    LSD
    psychedelic
    Psilocybin mushrooms
    psychedelic
  • Chemical class
    LSD
    lysergamide
    Psilocybin mushrooms
    tryptamine
  • Common dose
    LSD
    75–150 μg
    Psilocybin mushrooms
    1–2.5 g
  • Peak duration
    LSD
    180–300 min
    Psilocybin mushrooms
    60–150 min
  • Primary positives
    LSD
    Open- and closed-eye visuals (geometric patterns, breathing surfaces), Euphoria and feelings of awe, Introspection and insight
    Psilocybin mushrooms
    Open- and closed-eye visuals (often warmer and more "organic" than LSD), Euphoria and giddiness, Emotional intensity, often spiritual
  • Primary negatives
    LSD
    Anxiety, paranoia or panic (especially in poor set/setting), Confusion and difficulty with practical tasks, Mild physical tremor
    Psilocybin mushrooms
    Anxiety, paranoia or panic (especially with poor set/setting or high doses), Confusion and difficulty with practical tasks, Strong nausea, occasionally vomiting
  • Legal (DE)
    LSD
    illegal
    Psilocybin mushrooms
    illegal
  • Legal (NL)
    LSD
    illegal
    Psilocybin mushrooms
    illegal-tolerated
  • Legal (US)
    LSD
    schedule-1
    Psilocybin mushrooms
    schedule-1
  • Legal (UK)
    LSD
    class-a
    Psilocybin mushrooms
    class-a

Key harm-reduction difference

LSD and Psilocybin mushrooms differ most in their risk profiles and durations. Always research each independently before any session. If you are choosing between them based on safety alone, consult the full profiles and the interaction checker for any combinations you may be planning.

Related pages


FAQ.

Is LSD stronger than Psilocybin mushrooms?
"Stronger" depends on the metric. Compare dose ranges, subjective intensity, and duration side by side above. Always factor in individual tolerance.
Can I combine LSD and Psilocybin mushrooms?
Check the interaction checker for this specific pair. Many combinations carry serious risk even at low doses.
Which lasts longer, LSD or Psilocybin mushrooms?
Duration varies by route. See the comparison table above for peak and total duration by the most common route.
LSD vs Psilocybin mushrooms: which is safer?
Neither substance is "safe" in absolute terms. Harm is a function of dose, setting, purity, and individual factors. The comparison above covers the key risk differences.
Are LSD and Psilocybin mushrooms in the same drug class?
See the category and chemical class rows above. Substances in different classes often have very different risk profiles even if subjective effects overlap.
Is LSD legal where Psilocybin mushrooms is?
Legal status is substance- and jurisdiction-specific. See the legal status section for key countries.
Where can I get harm reduction info for LSD and Psilocybin mushrooms?
Each substance has a full profile on this site with dosage, interactions, testing, and legal information. Follow the links at the bottom of this page.
How do I test whether my substance is LSD or Psilocybin mushrooms?
Reagent testing can distinguish most substances. Check the reagent guide tool for expected color reactions for both.