opioid
Opioides dosage 2026: safe ranges by route and weight.
Opioides has 2 documented routes of administration. The most common is oral. Always start at the lowest dose range and wait the full onset window before redosing.
Dose ranges by route.
Oral
- Umbral
- 5 mg
- Ligera
- 10–30 mg
- Común
- 30–60 mg
- Fuerte
- 60–120 mg
- Pesada
- 120 mg
Esnifado
- Umbral
- 5 mg
- Ligera
- 5–20 mg
- Común
- 20–40 mg
- Fuerte
- 40–80 mg
- Pesada
- 80 mg
| Vía | Umbral | Ligera | Común | Fuerte | Pesada |
|---|---|---|---|---|---|
| Oral | 5 mg | 10–30 mg | 30–60 mg | 60–120 mg | 120 mg |
| Esnifado | 5 mg | 5–20 mg | 20–40 mg | 40–80 mg | 80 mg |
Empieza por abajo. Cuerpo, tolerancia y mezclas lo cambian todo.
Duration timeline.
Oral
total ~ 1320 min- Inicio
- 15–60 min
- Pico
- 60–180 min
- Bajada
- 3–6h
- Resaca
- 4–12h
Esnifado
total ~ 640 min- Inicio
- 1–10 min
- Pico
- 30–90 min
- Bajada
- 1.5–3h
- Resaca
- 3–6h
Bodyweight quick formula
For a 70 kg adult, divide the total mg dose by 70 to get your mg/kg ratio. Most published ranges assume this reference weight. If you weigh significantly less, reduce proportionally; significantly more does not always mean linearly higher doses.
Related pages
FAQ.
- What is a safe Opioides dose?
- A "safe" dose depends on body weight, tolerance, set and setting. Start at the threshold or light range for your chosen route and do not redose until onset is complete.
- How do I calculate Opioides dose by weight?
- For substances where bodyweight matters: divide the mg amount by your weight in kg to get the mg/kg ratio. Most common dose data assumes a 70–80 kg adult.
- What happens if I take too much Opioides?
- Exceeding the "heavy" range significantly increases risk of adverse effects, medical emergency, or overdose. Harm reduction starts with knowing the ranges.
- How long does Opioides last?
- Duration varies by route. The timeline section below shows onset, peak, offset and after-effects for each route.
- Can I mix Opioides with other substances?
- Many combinations are dangerous. Check the interaction checker tool before combining anything. Never combine on a first experience.
- Is Opioides dosage the same for all routes?
- No. Bioavailability differs significantly by route — intranasal and IV routes typically require lower doses than oral for equivalent effect.
- Should I weigh my Opioides dose?
- Always. A milligram scale (0.001g precision) is essential for most substances. Volumetric dosing with a solvent is the gold standard for sub-10mg doses.