Comparison
Amfetamine vs MDMA.
Side-by-side comparison of Amfetamine and MDMA — dosage, effects, duration, legal status, and key harm reduction considerations.
- CategoryAmfetaminestimulantMDMAempathogen
- Chemical classAmfetamineamphetamineMDMAsubstituted-amphetamine
- Common doseAmfetamine20–40 mgMDMA75–125 mg
- Peak durationAmfetamine120–240 minMDMA90–150 min
- Primary positivesAmfetamineStimulatie en wakkerheid, Verhoogde concentratie en motivatie, Zelfvertrouwen en spraakzaamheidMDMAEuforie, Emotionele warmte en openheid, Verhoogde empathie
- Primary negativesAmfetamineAngst en racende gedachten (vooral bij hogere doses), Slapeloosheid voor 6–12+ uur na laatste dosis, Cardiovasculaire belastingMDMAKaakklemmen (bruxisme), Uitdroging of hyponatriëmie door overmatig drinken, Hyperthermie in warme omgevingen
- Legal (DE)Amfetamineprescription-onlyMDMAillegal
- Legal (NL)AmfetamineillegalMDMAillegal-tolerated
- Legal (US)Amfetamineschedule-2MDMAschedule-1
- Legal (UK)Amfetamineclass-bMDMAclass-a
| Amfetamine | MDMA | |
|---|---|---|
| Category | stimulant | empathogen |
| Chemical class | amphetamine | substituted-amphetamine |
| Common dose | 20–40 mg | 75–125 mg |
| Peak duration | 120–240 min | 90–150 min |
| Primary positives | Stimulatie en wakkerheid, Verhoogde concentratie en motivatie, Zelfvertrouwen en spraakzaamheid | Euforie, Emotionele warmte en openheid, Verhoogde empathie |
| Primary negatives | Angst en racende gedachten (vooral bij hogere doses), Slapeloosheid voor 6–12+ uur na laatste dosis, Cardiovasculaire belasting | Kaakklemmen (bruxisme), Uitdroging of hyponatriëmie door overmatig drinken, Hyperthermie in warme omgevingen |
| Legal (DE) | prescription-only | illegal |
| Legal (NL) | illegal | illegal-tolerated |
| Legal (US) | schedule-2 | schedule-1 |
| Legal (UK) | class-b | class-a |
Key harm-reduction difference
Amfetamine and MDMA differ most in their risk profiles and durations. Always research each independently before any session. If you are choosing between them based on safety alone, consult the full profiles and the interaction checker for any combinations you may be planning.
Related pages
FAQ.
- Is Amfetamine stronger than MDMA?
- "Stronger" depends on the metric. Compare dose ranges, subjective intensity, and duration side by side above. Always factor in individual tolerance.
- Can I combine Amfetamine and MDMA?
- Check the interaction checker for this specific pair. Many combinations carry serious risk even at low doses.
- Which lasts longer, Amfetamine or MDMA?
- Duration varies by route. See the comparison table above for peak and total duration by the most common route.
- Amfetamine vs MDMA: which is safer?
- Neither substance is "safe" in absolute terms. Harm is a function of dose, setting, purity, and individual factors. The comparison above covers the key risk differences.
- Are Amfetamine and MDMA in the same drug class?
- See the category and chemical class rows above. Substances in different classes often have very different risk profiles even if subjective effects overlap.
- Is Amfetamine legal where MDMA is?
- Legal status is substance- and jurisdiction-specific. See the legal status section for key countries.
- Where can I get harm reduction info for Amfetamine and MDMA?
- Each substance has a full profile on this site with dosage, interactions, testing, and legal information. Follow the links at the bottom of this page.
- How do I test whether my substance is Amfetamine or MDMA?
- Reagent testing can distinguish most substances. Check the reagent guide tool for expected color reactions for both.