Comparison
MDMA vs Mefedron.
Side-by-side comparison of MDMA and Mefedron — dosage, effects, duration, legal status, and key harm reduction considerations.
- CategoryMDMAempathogenMefedronstimulant
- Chemical classMDMAsubstituted-amphetamineMefedroncathinone
- Common doseMDMA75–125 mgMefedron150–225 mg
- Peak durationMDMA90–150 minMefedron60–120 min
- Primary positivesMDMAEuforie, Emotionele warmte en openheid, Verhoogde empathieMefedronEmpathogene warmte, MDMA-achtig in lage dosis, Stimulerende euforie, Praatzucht en sociale lichtheid
- Primary negativesMDMAKaakklemmen (bruxisme), Uitdroging of hyponatriëmie door overmatig drinken, Hyperthermie in warme omgevingenMefedronStevige cravings, binge-patroon in één sessie, Vaatvernauwing (koude handen, blauwe vingers), Neusslijmvlies eraan bij vaak snuiven
- Legal (DE)MDMAillegalMefedronprohibited
- Legal (NL)MDMAillegal-toleratedMefedronschedule-2
- Legal (US)MDMAschedule-1Mefedronschedule-1
- Legal (UK)MDMAclass-aMefedronclass-b
| MDMA | Mefedron | |
|---|---|---|
| Category | empathogen | stimulant |
| Chemical class | substituted-amphetamine | cathinone |
| Common dose | 75–125 mg | 150–225 mg |
| Peak duration | 90–150 min | 60–120 min |
| Primary positives | Euforie, Emotionele warmte en openheid, Verhoogde empathie | Empathogene warmte, MDMA-achtig in lage dosis, Stimulerende euforie, Praatzucht en sociale lichtheid |
| Primary negatives | Kaakklemmen (bruxisme), Uitdroging of hyponatriëmie door overmatig drinken, Hyperthermie in warme omgevingen | Stevige cravings, binge-patroon in één sessie, Vaatvernauwing (koude handen, blauwe vingers), Neusslijmvlies eraan bij vaak snuiven |
| Legal (DE) | illegal | prohibited |
| Legal (NL) | illegal-tolerated | schedule-2 |
| Legal (US) | schedule-1 | schedule-1 |
| Legal (UK) | class-a | class-b |
Key harm-reduction difference
MDMA and Mefedron differ most in their risk profiles and durations. Always research each independently before any session. If you are choosing between them based on safety alone, consult the full profiles and the interaction checker for any combinations you may be planning.
Related pages
FAQ.
- Is MDMA stronger than Mefedron?
- "Stronger" depends on the metric. Compare dose ranges, subjective intensity, and duration side by side above. Always factor in individual tolerance.
- Can I combine MDMA and Mefedron?
- Check the interaction checker for this specific pair. Many combinations carry serious risk even at low doses.
- Which lasts longer, MDMA or Mefedron?
- Duration varies by route. See the comparison table above for peak and total duration by the most common route.
- MDMA vs Mefedron: which is safer?
- Neither substance is "safe" in absolute terms. Harm is a function of dose, setting, purity, and individual factors. The comparison above covers the key risk differences.
- Are MDMA and Mefedron in the same drug class?
- See the category and chemical class rows above. Substances in different classes often have very different risk profiles even if subjective effects overlap.
- Is MDMA legal where Mefedron is?
- Legal status is substance- and jurisdiction-specific. See the legal status section for key countries.
- Where can I get harm reduction info for MDMA and Mefedron?
- Each substance has a full profile on this site with dosage, interactions, testing, and legal information. Follow the links at the bottom of this page.
- How do I test whether my substance is MDMA or Mefedron?
- Reagent testing can distinguish most substances. Check the reagent guide tool for expected color reactions for both.