stimulant
Mefedron dosage 2026: safe ranges by route and weight.
Mefedron has 3 documented routes of administration. The most common is oral. Always start at the lowest dose range and wait the full onset window before redosing.
Dose ranges by route.
Oraal
- Drempel
- 50 mg
- Licht
- 75–150 mg
- Normaal
- 150–225 mg
- Sterk
- 225–350 mg
- Zwaar
- 350 mg
Gesnoven
- Drempel
- 15 mg
- Licht
- 30–60 mg
- Normaal
- 60–120 mg
- Sterk
- 120–175 mg
- Zwaar
- 175 mg
Rectaal
- Drempel
- 30 mg
- Licht
- 50–100 mg
- Normaal
- 100–175 mg
- Sterk
- 175–250 mg
- Zwaar
- 250 mg
| Toedieningsweg | Drempel | Licht | Normaal | Sterk | Zwaar |
|---|---|---|---|---|---|
| Oraal | 50 mg | 75–150 mg | 150–225 mg | 225–350 mg | 350 mg |
| Gesnoven | 15 mg | 30–60 mg | 60–120 mg | 120–175 mg | 175 mg |
| Rectaal | 30 mg | 50–100 mg | 100–175 mg | 175–250 mg | 250 mg |
Begin onderaan. Lichaam, tolerantie en combineren doen er allemaal toe.
Duration timeline.
Oraal
totaal ~ 510 min- Opkomst
- 30–60 min
- Piek
- 60–120 min
- Afbouw
- 60–90 min
- Nawerking
- 2–4h
Gesnoven
totaal ~ 405 min- Opkomst
- 5–15 min
- Piek
- 30–60 min
- Afbouw
- 45–90 min
- Nawerking
- 2–4h
Rectaal
totaal ~ 475 min- Opkomst
- 10–25 min
- Piek
- 60–120 min
- Afbouw
- 60–90 min
- Nawerking
- 2–4h
Bodyweight quick formula
For a 70 kg adult, divide the total mg dose by 70 to get your mg/kg ratio. Most published ranges assume this reference weight. If you weigh significantly less, reduce proportionally; significantly more does not always mean linearly higher doses.
Related pages
FAQ.
- What is a safe Mefedron dose?
- A "safe" dose depends on body weight, tolerance, set and setting. Start at the threshold or light range for your chosen route and do not redose until onset is complete.
- How do I calculate Mefedron dose by weight?
- For substances where bodyweight matters: divide the mg amount by your weight in kg to get the mg/kg ratio. Most common dose data assumes a 70–80 kg adult.
- What happens if I take too much Mefedron?
- Exceeding the "heavy" range significantly increases risk of adverse effects, medical emergency, or overdose. Harm reduction starts with knowing the ranges.
- How long does Mefedron last?
- Duration varies by route. The timeline section below shows onset, peak, offset and after-effects for each route.
- Can I mix Mefedron with other substances?
- Many combinations are dangerous. Check the interaction checker tool before combining anything. Never combine on a first experience.
- Is Mefedron dosage the same for all routes?
- No. Bioavailability differs significantly by route — intranasal and IV routes typically require lower doses than oral for equivalent effect.
- Should I weigh my Mefedron dose?
- Always. A milligram scale (0.001g precision) is essential for most substances. Volumetric dosing with a solvent is the gold standard for sub-10mg doses.