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Comparison

Cocaine vs MDMA.

Side-by-side comparison of Cocaine and MDMA — dosage, effects, duration, legal status, and key harm reduction considerations.

  • Category
    Cocaine
    stimulant
    MDMA
    empathogen
  • Chemical class
    Cocaine
    tropane
    MDMA
    substituted-amphetamine
  • Common dose
    Cocaine
    30–60 mg
    MDMA
    75–125 mg
  • Peak duration
    Cocaine
    15–30 min
    MDMA
    90–150 min
  • Primary positives
    Cocaine
    Confidence and self-assurance, Euphoria and stimulation, Talkativeness and sociability
    MDMA
    Euphoria, Emotional warmth and openness, Increased empathy
  • Primary negatives
    Cocaine
    Compulsive redosing ("the line is shorter than you remember"), Cardiovascular strain (heart attacks and strokes occur even in young users), Severe nasal damage with regular insufflation
    MDMA
    Jaw clenching (bruxism), Dehydration or, conversely, hyponatremia from overhydration, Hyperthermia in warm environments
  • Legal (DE)
    Cocaine
    illegal
    MDMA
    illegal
  • Legal (NL)
    Cocaine
    illegal
    MDMA
    illegal-tolerated
  • Legal (US)
    Cocaine
    schedule-2
    MDMA
    schedule-1
  • Legal (UK)
    Cocaine
    class-a
    MDMA
    class-a

Key harm-reduction difference

Cocaine and MDMA differ most in their risk profiles and durations. Always research each independently before any session. If you are choosing between them based on safety alone, consult the full profiles and the interaction checker for any combinations you may be planning.

Related pages


FAQ.

Is Cocaine stronger than MDMA?
"Stronger" depends on the metric. Compare dose ranges, subjective intensity, and duration side by side above. Always factor in individual tolerance.
Can I combine Cocaine and MDMA?
Check the interaction checker for this specific pair. Many combinations carry serious risk even at low doses.
Which lasts longer, Cocaine or MDMA?
Duration varies by route. See the comparison table above for peak and total duration by the most common route.
Cocaine vs MDMA: which is safer?
Neither substance is "safe" in absolute terms. Harm is a function of dose, setting, purity, and individual factors. The comparison above covers the key risk differences.
Are Cocaine and MDMA in the same drug class?
See the category and chemical class rows above. Substances in different classes often have very different risk profiles even if subjective effects overlap.
Is Cocaine legal where MDMA is?
Legal status is substance- and jurisdiction-specific. See the legal status section for key countries.
Where can I get harm reduction info for Cocaine and MDMA?
Each substance has a full profile on this site with dosage, interactions, testing, and legal information. Follow the links at the bottom of this page.
How do I test whether my substance is Cocaine or MDMA?
Reagent testing can distinguish most substances. Check the reagent guide tool for expected color reactions for both.