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opioid

Opioïdes dosage 2026: safe ranges by route and weight.

Opioïdes has 2 documented routes of administration. The most common is oral. Always start at the lowest dose range and wait the full onset window before redosing.

Dose ranges by route.

Oral
Seuil
5 mg
Léger
10–30 mg
Courant
30–60 mg
Fort
60–120 mg
Lourd
120 mg
Sniffé
Seuil
5 mg
Léger
5–20 mg
Courant
20–40 mg
Fort
40–80 mg
Lourd
80 mg

Commence par le bas. Le corps, la tolérance et les mélanges changent tout.

Duration timeline.

Oral

total ~ 1320 min
Montée: 15–60 minPic: 60–180 minDescente: 3–6hAprès-effets: 4–12h
Montée
15–60 min
Pic
60–180 min
Descente
3–6h
Après-effets
4–12h

Sniffé

total ~ 640 min
Montée: 1–10 minPic: 30–90 minDescente: 1.5–3hAprès-effets: 3–6h
Montée
1–10 min
Pic
30–90 min
Descente
1.5–3h
Après-effets
3–6h

Bodyweight quick formula

For a 70 kg adult, divide the total mg dose by 70 to get your mg/kg ratio. Most published ranges assume this reference weight. If you weigh significantly less, reduce proportionally; significantly more does not always mean linearly higher doses.

Related pages


FAQ.

What is a safe Opioïdes dose?
A "safe" dose depends on body weight, tolerance, set and setting. Start at the threshold or light range for your chosen route and do not redose until onset is complete.
How do I calculate Opioïdes dose by weight?
For substances where bodyweight matters: divide the mg amount by your weight in kg to get the mg/kg ratio. Most common dose data assumes a 70–80 kg adult.
What happens if I take too much Opioïdes?
Exceeding the "heavy" range significantly increases risk of adverse effects, medical emergency, or overdose. Harm reduction starts with knowing the ranges.
How long does Opioïdes last?
Duration varies by route. The timeline section below shows onset, peak, offset and after-effects for each route.
Can I mix Opioïdes with other substances?
Many combinations are dangerous. Check the interaction checker tool before combining anything. Never combine on a first experience.
Is Opioïdes dosage the same for all routes?
No. Bioavailability differs significantly by route — intranasal and IV routes typically require lower doses than oral for equivalent effect.
Should I weigh my Opioïdes dose?
Always. A milligram scale (0.001g precision) is essential for most substances. Volumetric dosing with a solvent is the gold standard for sub-10mg doses.